Vaccines
We offer a wide range of effective and safe vaccines, including vaccines for STI prevention (hepatitis, gonococcus and human papillomavirus), as well as shingles and the new triple combination vaccine (MMR vaccine).
For vaccines required for overseas travel or study abroad, please see Travel Medicine.
Vaccines That Can Prevent STIs
We offer the following vaccines for STI prevention (hepatitis, gonococcus and human papillomavirus).
Hepatitis Vaccine
Prevents viral hepatitis caused by hepatitis viruses, the most common form of hepatitis in Japan. We offer hepatitis A, hepatitis B and hepatitis A and B combination vaccines.
Gonorrhea (Meningococcal Group B) Vaccine
Meningococcus and gonococcus are genetically very similar, and vaccination with the meningococcal B vaccine has been reported to potentially prevent gonorrhea.
HPV Vaccine
HPV not only causes cervical cancer but is also a cause of other cancers and warts (condyloma). We offer the HPV 9-valent vaccine.
The most common form of hepatitis in Japan is viral hepatitis caused by hepatitis viruses.
Hepatitis vaccines are effective for prevention. We offer the hepatitis A vaccine, the hepatitis B vaccine and a combination vaccine.
This is a vaccine reported to have a possible preventive effect against gonorrhea. Meningococcus and gonococcus are genetically very similar, and vaccination with the meningococcal B vaccine is suggested to have a preventive effect against gonorrhea.
This vaccine prevents HPV infection. HPV is well known as the virus that causes “cervical cancer”, but it also causes other cancers and warts (condyloma).
We offer the HPV 9-valent vaccine.
Routes of Transmission
The routes of transmission for hepatitis A virus, hepatitis B virus, gonococcus and HPV are as follows.
Infection occurs by consuming water or raw foods (shellfish, etc.) contaminated with the virus, or via stool containing the virus through anal intercourse or sexual activity involving licking around the anus.
Transmission is possible through acts such as oral sex, rimming (licking the anus) and licking hands that have touched the anus.
It is spread through blood and vaginal fluids containing the virus, so infection occurs through sexual contact and anal intercourse.
Gonococcus is transmitted through sexual contact, including oral sex. Note that gonococcus infects not only the genitals but also the throat and anus.
HPV is a virus transmitted mainly through sexual contact, and it is a common virus that more than 50 percent of women with sexual experience are said to contract at least once in their lifetime.
More than 80% of women and more than 90% of men may become infected with some form of HPV during their lifetime. (Even when infection occurs, the virus is sometimes cleared naturally by one’s own immunity.)
Who Is Eligible for Vaccination
Those eligible for vaccination are as follows.
For hepatitis B, infection through sexual contact has been increasing in recent years. Apart from cases such as needlestick injuries, most infections in adults are said to occur through sexual activity.
It can also be transmitted through kissing and oral sex, and because infection often causes no symptoms, infected people may be unaware that they carry the virus and pass it on to others without realizing it.
Hepatitis A / hepatitis B vaccine:
– Those with multiple sexual partners (including oral sex)
– Those who have a sexual partner with hepatitis B, or who live in the same household as someone with hepatitis B
– Those planning to travel overseas
– Healthcare workers, etc.
Gonorrhea vaccine:
– Those who have previously had gonorrhea or another STI
– Those who are allergic to the first-line drug for gonorrhea treatment (ceftriaxone)
– Those who have multiple sexual partners
– Those with a particularly high chance of infection, such as CSWs (people working in the sex industry, the adult video industry, etc.)
HPV vaccine:
– Those aged 9 or older who want to reduce their risk of HPV infection
(Because HPV vaccination also helps prevent penile cancer, anal cancer, etc., Western countries recommend vaccination not only for women but also for men)
HPV infection causes a variety of cancers, and we recommend vaccination for those who want to prevent cancer or prevent warts (condyloma).
Male genitals: penile cancer
Female genitals: cervical cancer, vulvar cancer and vaginal cancer
Common to both: oropharyngeal cancer and anal cancer
Vaccine Effectiveness
The effectiveness of the vaccines we offer is as follows.
With Havisure®, an imported hepatitis A vaccine, immunity can be expected from after the first dose, and a 2nd dose is given 6 months later to obtain long-term immunity.
Aimmugen®, a domestically produced hepatitis A vaccine, is normally given as 3 doses. The third dose is expected to maintain immunity over a longer term.
With inactivated hepatitis A vaccines, immunity is thought to persist over a long period once the prescribed number of doses is completed.
Immunity acquired by receiving the domestic hepatitis B vaccine (Bimmugen®) has been confirmed to last for at least 15 years. Effectiveness declines as the age at vaccination rises; for example, among people over 40, about eighty percent are said to acquire immunity from the vaccine.
The vaccine’s effectiveness is recognized by the government as well, and since 2016 it has been covered by routine vaccination for infants.
On the other hand, those born on or before March 31, 2016 did not receive routine vaccination, and so have not been vaccinated. (Except for those who received voluntary vaccination on their own.)
In some studies, administration of the gonorrhea vaccine has been reported to prevent gonorrhea by 51%. Syphilis, gonorrhea and chlamydia are also known to be preventable with a medication (oral) called Doxy-PEP, which can be considered for combined use as another prevention option.
At present, there is no medication to treat HPV once infection has occurred. Prevention through vaccination is therefore effective.
According to findings published by the CDC (Centers for Disease Control and Prevention) in the United States, cases of cervical cancer among girls aged 13 to 19 fell by as much as 83 percent, and among those aged 20 to 24 they fell by 66 percent.
Precancerous lesions also decreased in cervical cancer screening among girls in their 10s and 20s.
Condyloma of the genitals and anus in both men and women has also decreased markedly in every age group, and HPV vaccination for men is being promoted as well.
HPV vaccination is not only for women — it is also highly effective for men.
Mainly, the following 2 benefits can be expected.
– Prevention of diseases caused by HPV infection in the man himself (condyloma and cancers such as penile cancer)
– Reducing a partner’s risk of HPV infection by not becoming a source of infection yourself
Receiving the HPV vaccine helps protect both yourself and your partner!
Prices and Vaccination Schedule
The vaccination price and schedule for each vaccine are as follows.
All vaccines are prescribed as self-pay care.
Product name: Havisure
Cost: 13,000 yen per dose (tax included)
Number of doses: 2 doses
Schedule: First dose, 6 months later
Product name: Aimmugen
Cost: 16,500 yen per dose (tax included)*
Number of doses: 3 doses
Schedule: First dose, 1 month later, 6 months later
*Patients who started the Aimmugen vaccination series at our clinic on or before July 22, 2026 may continue to receive it at the previous price.
Product name: Bimmugen
Cost: 7,000 yen per dose (tax included)
Number of doses: 3 doses
Schedule: First dose, 1 month later, 6 months later
The acquired immunity has been confirmed to last at least 15 years. The effectiveness decreases as the age at vaccination increases; for example, it is said that about eighty percent of people over 40 acquire immunity through the vaccine.
An antibody test is carried out 1 to 2 months after the 3 doses, and if no antibody response appears, an additional dose may be given.
Product name: Twinrix
Cost: 13,000 yen per dose (tax included)
Number of doses: 3 doses
Schedule: First dose, 1 month later, 6 months later
Product name: Bexsero
Cost: 25,000 yen per dose (tax included)
Number of doses: 2 doses
Schedule: First dose, 1 month later
Doxy-PEP can be considered as a combined option alongside another prevention method.
Patients who receive the gonorrhea vaccine at our clinic can be tested free of charge for gonorrhea and chlamydia (at 3 sites: genital, throat and anal) at the time of the first and second doses (normally valued at 20,000 yen).
In addition, for one year from the date of the first dose, even outside of vaccination visits, you can be tested for gonorrhea and chlamydia (at 3 sites: genital, throat and anal) for 3,000 yen (tax included).
This testing can only be provided as self-pay care (care outside insurance coverage). In accordance with the Ministry of Health, Labour and Welfare’s principle that mixed billing is prohibited, please understand that treatment will also be self-pay.
Product name: Gardasil 9
Cost: 30,000 yen per dose (tax included)
Number of doses: 3 doses (or 2 doses)
Schedule: First dose, 2 months later, 6 months later (or first dose, 6 months later)
It has been reported that the HPV 9-valent vaccine can be expected to provide sufficient effectiveness even without receiving all 3 doses. (For more details, see here)
Our clinic also recommends a 2-dose regimen.
There are three types of HPV vaccine—2-valent, 4-valent and 9-valent—and this number represents the number of types the vaccine protects against.
There are more than 180 types of HPV, and the diseases that may develop differ depending on the type of infection.
At our clinic,
– Prevention of condyloma is possible with either the 4-valent or 9-valent vaccine
– Compared to the 4-valent vaccine, the 9-valent vaccine offers a markedly higher preventive effect against cancer and condyloma (4-valent: approximately 60%, 9-valent: approximately 90%)
For these reasons, we have adopted the 9-valent HPV vaccine.
Vaccination Around the Same Time as Other Vaccines
All vaccines for STI prevention can be given on the same day.
There are no particular restrictions when other vaccines are given around the same time, so please rest assured.
You can also discuss your vaccination schedule in detail with our doctor.
The figure is quoted from the notice on the revision of the rules for vaccination intervals on the Ministry of Health, Labour and Welfare website
For details, please refer to this page of the Ministry of Health, Labour and Welfare.
Consultation Flow
The process for a consultation for vaccination at our clinic is as follows.
Medical Interview and Consultation with a Doctor
After discussing with the doctor, we will consider whether vaccination is possible.
Vaccination and Payment
You receive the vaccination and complete payment. A consultation fee applies for the first vaccination, but from the 2nd dose onward you can receive the vaccine without a consultation (and no consultation fee applies).
We also provide testing, treatment and prevention for STIs.