PrEP/PEP Delivery

We have been conducting ‘One-Coin Testing’ aimed at the early detection of HIV since the opening of our clinic.

For HIV can now be prevented with medication, we have been actively prescribing and educating about PrEP (pre-exposure prophylaxis) and PEP (post-exposure prophylaxis) for HIV prevention.

Teleprescription for PEP have been available since July 2023, making it easier for people from distant areas to access generic PEP.

We now also offer teleprescription consultations for PrEP.

Our clinic is the only one in Kansai region recognized by PrEP in Japan, the Ministry of Health, Labour and Welfare’s AIDS Policy Research Project.

To make an appointment, please proceed from ‘PrEP・PEP オンライン診療 [Teleprescription for PrEP/PEP]’ on the rich menu of our official LINE account.

Those not using LINE may directly make an appointment from our website below.

IMMEDIATE in-hospital prescription of PrEP/PEP is available throughout our open hours.

Patients who purchase PrEP at our clinic can contact us 24/7 via LINE with any questions about PrEP interactions with other medications, how to take PrEP, and more. Please don’t hesitate to reach out.

Also, We can prescribe medications for ED, AGA, premature ejaculation, contraceptive pills, morning-after pills and clinic-exclusive cosmetics alongside PrEP/PEP.

If the tests result positive, treatment medication can also be prescribed online.

The following services are currently offered exclusively for those using PrEP/PEP teleprescription: teleprescriptions of medication for ED, AGA medication, premature ejaculation treatment, contraceptive pills, morning-after pills or clinic-exclusive cosmetics.

Please consider visiting us to take face-to-face consultation.

Partner clinic in Tokyo

Residents of Hokkaido, Tohoku or Kanto region can have a quicker access to PEP at our partnered Personal Health Clinic in Tokyo. Visit their website for more details.

Please select the section to jump.

Note that the prices indicated in this page are all inclusive of tax.

PrEP Teleprescription

What is PrEP?

PrEP (pre-exposure prophylaxis) is the use of an HIV-prevention medication before a potential exposure to HIV such as sexual activities to reduce the risk of HIV acquisition. This prevention method is recommended especially for those at high risk of HIV infection. PrEP is a preventative method that, unlike condoms which rely on the partner’s intention, allows you to take control of your own protection by taking the medication for yourself. This approach is now even endorsed by WHO, the World Health Organization. We offer a few kinds of generic PrEP at an affordable price as well as follow-up medical check-ups, so please feel free to contact us!

Always ensure that you undergo appropriate tests when starting and/or continuing PrEP. Prescriptions from facilities that do not conduct various tests, or personal imports without testing, carry the significant risk of HIV resistance and worsening of hepatitis B.

Price of PrEP Teleprescription

Cost calculation

[Total Cost] = [Consultation Fee*] +
[Shipping Fee] + [Package Price]

* First visit: 2,500 JPY,
2nd+ visit: 1,000 JPY

Note that PrEP prescription requires doctor’s consulation.

About Shipping Fees

PrEP teleprescription incurs round-trip shipping fees of 1,000 JPY.

* In case of only shipping medication, the fee is 500 JPY for one-way shippment.

1-Month Package of PrEP

Price: 11,000 JPY

Including:

– 1 bottle of PrEP (30 tablets), Descovy or Truvada

– HIV rapid test

– Hepatitis B rapid test

– Syphilis test (results notified via e-mail)

3-Month Package of PrEP

Price: 22,000 JPY

Including:

– 3 bottles of PrEP (90 tablets), Descovy or Truvada

– HIV rapid test

– Hepatitis B rapid test

– Syphilis test (results notified via e-mail)

6-Month Package of PrEP

Price: 43,000 JPY

Including:

– 6 bottles of PrEP (180 tablets), Descovy or Truvada

– HIV rapid test

– Hepatitis B rapid test

– Syphilis test (results notified via e-mail)

– Extra test kit to use 3 months after (HIV, hepatitis B and syphilis)

As part of our efforts to further reduce the risk of HIV infection, we offer free syphilis testing and a discount for gonorrhea and chlamydia testing for those prescribed PrEP/PEP at our clinic.

PrEP Limited Option

Gonorrhea and Chlamydia (genitals, throat, anus): 3,000 JPY (normally 20,000 JPY)

Discharge test (vaginal candida, vaginal trichomonas and bacterial vaginosis): 3,000 JPY (normally 4,500 JPY)

We can also prescribe medications for ED, AGA, premature ejaculation, contraceptive pills, morning-after pills and clinic-exclusive cosmetics alongside PrEP/PEP.

If the tests result positive, treatment medication can also be prescribed online.

The following services are currently offered exclusively for those using PrEP/PEP teleprescription: teleprescriptions of medication for ED, AGA medication, premature ejaculation treatment, contraceptive pills, morning-after pills or clinic-exclusive cosmetics.

Please consider visiting us to take face-to-face consultation.

Process of PrEP Teleprescription

Step 1

Make an appointment via LINE

Select “PrEP・PEP 電話診療 [PrEP/PEP Teleprescription]” from the rich menu on the official LINE, and make an appointment.

Step 2

Fill in the consultation form

Please be sure to fill out the questionnaire in advance.

Step 3

Register Credit Card Information

48 hours before your appointment, we will send an e-mail about credit card registration to your registered e-mail address.

Once registered, we will provisionally reserve your credit card limit according to the desired prescription drugs and quantity. Please be assured that payment has not yet made at this time.

Bank transfer is also available.

A credit card is recommended to use as registering a debit card might temporarily withdraw some amount from your account. Also, depending on your smartphone app, it may show a ‘Payment Completed’ notification, but rest assured that this is only a provisional hold. Our doctor notify you when the payment is made.

Credit Cards
Available

Visa / Mastercard® / American Express®

Step 4

Delivery of PrEP

We will ship your order as soon as possible after the payment is completed.

Step 5

Receive Medication and Test Kits

You will receive the mailed items after the payment is confirmed.

You can designate the address for delivery as you like such as at your home, workplace or a designated post office/Yamato business office.

Step 6

Conduct Tests and Taking Medication

Use test kits as instructed in the manual.

After returning the samples, you can check the results by e-mail in 3 to 5 days after they reach our clinic.

Frequently Asked Questions

What is the difference between generic and brand-name PrEP?

Generic medicines are released after the patent for the brand-name medicine has expired. They contain the same active ingredients, quality, efficacy and safety as the brand-name medicines have. The brand-name PrEP tablets are quite expensive, costing approximately 110,000 JPY for a month. To provide our patients with a more affordable option, we adopt generic PrEP medication.

How can you offer PrEP at a lower price?

We adopt generic medicines and strive to offer medications at an affordable price whenever possible. This is because we have a strong desire to promote the availability of HIV prevention medications in Japan for the purpose of promoting social commitment.

There are 2 kinds of medicine. Which one is better?

Generic medicines of Truvada are common, but recently generic medicines of Descovy are being used more often. Descovy is a newer medicine than Truvada, with fewer known side effects in renal function and bone density. Please consult our doctor for more details.

Which is better, daily or on-demand?

If you have sex twice a month or more, we recommend daily use. Even if you forget to take it by chance, the daily use reduces the risk of HIV more than on-demand PrEP does.

Is a condom necessary even if I take PrEP?

PrEP can only prevent HIV acquisition but not effective for other STDs. Thus, it is still recommended to use condoms during sex and take other measures to prevent STDs even with PrEP.

I forgot to take my medication. What should I do?

Take medication immediately as soon as you realize you’ve forgotten to take it, and resume your medication at the usual time from the following day.

How should I store my medication?

The medicine is in a bottle with a desiccant. Please store the bottle at room temperature. Be careful not to leave it in a cold or warm environment such as in the refrigerator or in a hot car.

PEP Teleprescription

What is PEP?

It is crucial to start taking PEP to minimize your risk within 72 hours after potential exposure to HIV. With consideration of possible delay in delivery, come visit us if possible.

PEP, post-exposure prophylaxis, is an immediate preventive measure that involves taking medication within 72 hours after a potential exposure to HIV, such as unprotected sex with someone who is HIV positive or at risk of HIV infection.

Proper usage of the medication can reduce the risk of HIV infection to nearly zero, but it is essential to confirm a negative HIV and Hepatitis B status before starting the treatment.

Brand-name PEP is extremely expensive, costing around 10,000 yen per tablet. And clinics offering brand-name PEP normally charge around 300,000 yen, including initial consultation and testing fees. We offer generic PEP, which is significantly more affordable, and the package includes rapid blood tests and follow-up care at approximately quarter of the cost of brand-name PEP.

Recommended for those:

– Engaged in sex without proper protection

– Experienced condom breakage during sex

– Who had sex with multiple partners

– Engaged in sexual contact with an HIV-positive individual

– Sexually assaulted

– Involved in needlestick injury

Contraindicated to those:

– Whose sexual partners have tested negative for HIV

– Already being HIV positive

– Who have tested positive for hepatitis B (as PEP may worsen the condition)

HIV Transmission Risk

The approximate risk of HIV transmission varies depending on the type of sexual activity and whether you are the insertive or receptive partner.

The likelihood of HIV transmission is not high, but the number of tests has decreased in recent years, increasing the possibility of unaware HIV-positive individuals.

Moreover, the number of new patients who develop AIDS suddenly, without prior recognition, has slightly increased in 2020 compared to the significant decrease in testing, necessitating caution.

For those not regularly taking HIV preventive medication (PrEP) and engaging in activities that could lead to HIV infection, the only way to minimize the risk to nearly zero is by taking PEP.

Estimated HIV
Transmission Rates

Needle Stick: 0.3%

Anal Intercourse (Receptive Partner): 1.38%

Anal Intercourse (Insertive Partner): 0.11%

Vaginal Intercourse (Female Partner): 0.08%

Vaginal Intercourse (Male Partner): 0.04%

Oral Sex: Almost no risk

Biting: No data in literature

Price of PEP Teleprescription

We prescribe generic PEP at approximately quarter of the cost of brand-name PEP which costs around 300,000 JPY for total medication (10,000 JPY per tablet).

PEP Package: 78,500 JPY

We accept credit card or bank transfer for a payment.

* PEP package (77,000 JPY) + shipping fee (1,500 JPY)

What is included:

– Consultation Fee

– 30 tablets of generic PEP (including 2 extra tablets)

– 2 Test kits

– 2 envelopes for returning test kits

* The instructions of test kits are included in the package.

We can also prescribe medications for ED, AGA, premature ejaculation, contraceptive pills, morning-after pills and clinic-exclusive cosmetics alongside PrEP/PEP.

If the tests result positive, treatment medication can also be prescribed online.

Process of PEP Teleprescription

Step 1

Make an appointment via LINE

Select “PrEP・PEP 電話診療 [PrEP/PEP Teleprescription]” from the rich menu on the official LINE, and make an appointment.

Step 2

Fill in the consultation form

Please be sure to fill out the questionnaire in advance.

Step 3

Register Credit Card Information

48 hours before your appointment, we will send an e-mail about credit card registration to your registered e-mail address.

Once registered, we will provisionally reserve your credit card limit according to the desired prescription drugs and quantity. Please be assured that payment has not yet made at this time.

A credit card is recommended to use as registering a debit card might temporarily withdraw some amount from your account. Also, depending on your smartphone app, it may show a ‘Payment Completed’ notification, but rest assured that this is only a provisional hold. Our doctor notify you when the payment is made.

Credit Cards
Available

Visa / Mastercard® / American Express®

Step 4

Doctor’s consultation via phone

Our doctor will call you at around your appointed time and assess your suitability for PEP during the consultation. Please note that the timing might slightly shift due to the clinic’s schedule.

Step 5

Receive Medication and Test Kits

You will receive the mailed items after the payment is confirmed.

You can designate the address for delivery as you like such as at your home, workplace or a designated post office/Yamato business office.

Step 6

Conduct Tests and Taking Medication

Use test kits as instructed in the manual, take a picture of the result and then send it to us via LINE.

After the doctor’s approval, start taking PEP. Please use the provided return envelope to send back the first test kit to us.

After returning the samples, you can check the results by e-mail in 3 to 5 days after they reach our clinic.

If you test positive for HIV or hepatitis B, you won’t be able to take PEP.

Step 7

Re-test and return the second test kit after completing PEP

After taking PEP for 28 days, perform the test using the second test kit. Take a picture of the results and send it to us via LINE or e-mail.

Also, please use the provided return envelope to send the second test kit back to us.

Frequently Asked Questions

What is the difference between PEP and PrEP?

PEP involves taking medication “after” a potential exposure to HIV, while PrEP is taken continuously “before” sexual contact to prevent HIV.

How effective is PEP?

Since the introduction of PEP, there have been no reported cases of HIV transmission in advanced countries among healthcare workers who experienced needle stick injuries (accidental self-injection of a needle contaminated with HIV), which is known to entail a higher risk than sexual contacts. Starting PEP as soon as possible significantly increases the effectiveness of HIV prevention.

I’m unsure whether I should take PEP. Is it necessary?

If you have had a contact or potential exposure to bodily fluids (such as semen, vaginal secretions, blood, etc.) from an HIV-infected individual, it is advisable to consider taking PEP. However, please consult a doctor for a specific assessment.

What is the difference between generic and brand-name PEP?

Generic drugs are released after the patent for the brand-name medication has expired. They contain the same active ingredients, quality, efficacy and safety as the brand-name medication. The brand-name PEP tablets are quite expensive, costing approximately 10,000 yen per tablet. To provide our patients with a more affordable option, we offer generic PEP medication.

How can you offer PEP at a lower price?

We utilize generic drugs to reduce costs and strive to offer medication at an affordable price whenever possible. This is because we have a strong desire to promote the availability of HIV prevention medications in Japan for the purpose of promoting social commitment.

Can I take the prescribed PEP medication abroad?

Please check the laws and regulations of your destination, as the regulations may vary depending on countries and regions.

Do you provide medical consultations over the phone?

For the sake of patient safety and accurate prescription, we do not offer telemedicine consultations for PEP prescriptions. If you would not be able to start PEP within 72 hours after a potential exposure due to our business hours, please contact us through our official LINE account.

May I grind the tablets and take them?

It is not recommended because crushing the tablets may result in a bitter taste, and there is no available data on the absorption when the tablets are crushed.

Is there a specific time to take the medication?

PEP should be started within 72 hours after a potential exposure, and the earlier it is started, the higher the preventive effect. However, there is no specific time of day designated for taking the medication.

Are there any side effects?

Reported side effects include nausea, insomnia, irritability, dizziness, and others. In most cases, these side effects are mild. If you have any concerns, please consult with our doctors.

I missed a dose. What should I do?

If you realize you missed a dose, take one dose as soon as possible. However, if the next regular dose is approaching (typically within 12 hours), skip the missed dose and take one dose at the next regular dosing time. Under no circumstances should you take two doses at once.

Are there any beverages that should be avoided?

There are no specific restrictions. However, it is advised to avoid consuming alcohol before or after taking the medication.

I vomited after taking the pill. What should I do?

If you vomit after taking the medication, do not take another dose. Once you feel better, try to take the medication at the next scheduled dosing time. Drinking plenty of water may help alleviate nausea.

Are there any medications or dietary supplements that should not be taken together?

Please avoid consuming products containing St. John’s Wort, as they may reduce the effectiveness of the medication. Additionally, supplements containing minerals such as aluminum, magnesium, iron or calcium may also diminish the effects of the medication.

I have heared 2 tablets for one dose. Is 1 tablet sufficient?

PEP necessitates the intake of three different components, and depending on the healthcare institution, multiple medications may be prescribed to cover all three. However, the PEP medication provided at our clinic contains all the necessary components in a single tablet.

What are 2 extra tablets for?

The medication we prescribe at our clinic comes in a bottle with 30 tablets, leaving 2 tablets as extras. After completing the 28-day course, please dispose of the remaining tablets. It is acceptable to take the additional 2 tablets over the following 2 days if desired, but there is currently no evidence to suggest that taking a total of 30 tablets enhances the effectiveness.

This article is supervised by:

Dr. Daisuke SHIOJIRI

Director of Personal Health Clinic, Doctor of Medicine.
Providing medically accurate knowledge and compassionate care at National Center for Global Health and Medicine (Shinjuku, Tokyo) and Personal Health Clinic, focusing on STIs such as HIV and PrEP.
Born in Japan and raised in Kenya, Africa, he is also licensed to practice in Kenya, where he participates in medical and educational support activities.
He also serves as a visiting doctor at our clinic.